|
| |
| | Patent 5744161: Use of piperine as a bioavailability enhancer |
 | | The probable mechanism of piperine's effect on the bioavailability of beta-carotene is its effect on gastrointestinal events that lead to increased absorption of this nutrient and most probably other nutrients as well. | | | As a daily supplement taken with a nutrient or is nutrients by an average healthy adult, piperine is effective and safe in a broad dose range. | | | Additional evidence from the experiment with 14 day supplementation of beta-carotene to 12 healthy volunteers show that piperine does not affect absorption, metabolism and elimination of nutrients that are not supplemented, but otherwise consumed with a daily food. |
|
http://www.freepatentsonline.com/5744161.html
|
|
| |
| | EPA: Pesticides - Piperine (043501) Fact sheet |
| | Piperine’s unpleasant odor and taste make it effective in products designed to repel mammals such as dogs, cats, squirrels, and skunks. | | | Use Sites: The first registered pesticide product containing piperine as an active ingredient is a mammalian repellent for residential use in non-food areas. | | | Humans are regularly exposed to piperine in various products, including food. |
|
http://www.epa.gov/oppbppd1/biopesticides/ingredients/factsheets/factsheet_043501.htm
|
|
| |
| | piperine NYS DEC Letter - Registration of Havahart Critter Ridder 11/04 |
| | The active ingredients oil of black pepper and piperine both occur naturally in foods and are used as direct food additives, and are considered to be "generally recognized as safe" by the USFDA. | | | Product should not be applied to shrubs or soft-bodied ornamentals and may not be used on food or feed crops. | | | Risks to users of the Havaharto product should be minimal given the granular formulation of the product and the label requirement that handlers wear gloves. |
|
http://pmep.cce.cornell.edu/profiles/rodent/piperine/piperine_let_1104.html
|
|
| |
| | Where is Piperine Found |
| | Piperine makes up about 5-7% of the peppercorns, and although it is only found in nature with a 98% purity it is a very abundant chemical. | | | The plant is known for its broad shiny green leaves, and small flowers. | | | The pepper vine is indigenous to the Malabar Coast of India, but is also grown in other parts of southern Asia, South America and even Africa. |
|
http://web1.caryacademy.org/chemistry/rushin/StudentProjects/CompoundWebSites/2000/Piperine/where_is_piperine_found.htm
|
|
| |
| | [No title] |
| | Egg fertilization and polyspermia was decreased by 0.18-1.05 mM piperine dose-dependently. | | | A new insecticidal amide piptigrine (1) possessing highly extended conjugation was isolated from the dried ground seeds of Piper nigrum along with the known amides piperine and wisanine. | | | Extraction of ginger, black pepper, & chili powder using near-critical carbon dioxide, propane, and dimethyl ether to determine yield and extraction efficiency revealed that yield of piperines obtained by propane extraction of black pepper was only 10% of that achieved with dimethyl ether & CO(2). |
|
http://www.herbmed.org/viewherb.asp?varHerb_ID=111
|
|
| |
| | Piperine Report |
| | Thermogenesis, the process of generating energy in the cell, enables the body to properly utilize the foods and nutrients taken in daily. | | | This in turn will and does increase the metabolic processes, and that pathway leads to an increased, created demand for additional nutrients and energy, which are necessary for increased and proper efficiency of metabolism. | | | As the body ages, the intestines become less and less efficient in their absorption capacity. |
|
http://www.cochranfoundation.com/reports/piperin.htm
|
|
| |
| | Zunaoe Science & Technology Development Co. Ltd. Piperine |
| | Piperine is an indispensable additive in many medicines, in wine-making industry and food industry. | | | It is gratifying that piperine, as a new natural food additive, are being used to replace chemical synthetic, which is to become an unresistant trend throughout the world. | | | Piperine, processed through advanced scientific methods, can be widely used in modern medicine manufacture. |
|
http://zunaoe.ebigchina.com/sdp/150248/4/md-462303/98063.html
|
|
| |
| | British Pharmaceutical Codex 1911: PIPER NIGRUM, B.P., piperidine, piperidine tartrate, piperine |
| | By this means, that portion of the pericarp, exterior to the fibrovascular bundles that traverse the fruit from base to apex, is removed. | | | White pepper is greyish-white in colour, and exhibits vertical lines (fibrovascular bundles); it contains less piperine than black pepper, and is less pungent. | | | Pepper is a diuretic, and is sometimes used in place of cubebs in gonorrhoea and urethritis, but is apt to irritate. |
|
http://www.ibiblio.org/herbmed/eclectic/bpc1911/piper-nigr.html
|
|
| |
| | Bioperine - Black pepper extract may enhance your nutrient absorption |
| | Piperine may promote rapid absorption of nutrients from the gastrointestinal tract. | | | Bioperine is an extremely pure and safe nutritional supplement of piperine, an alkaloid from the fruits of the black pepper plant (Piper nigrum). | | | Piperine is the active constituent responsible for pepper's ability to increase the bioavailability of nutrients. |
|
http://www.discount-vitamins-herbs.net/bioperine.htm
|
|
| |
| | Centreforce Phytofood Joints |
| | Piperine is a component of black pepper and has been known for improving nutrient absorption. | | | Similar increases in absorption have been found for many other nutrients. | | | The results showed 5mg/day dose of piperine taken with 15mg beta-carotene resulted in a 60% increase in serum beta-carotene levels compared with placebo. |
|
http://health.centreforce.com/health/Joints.html
|
|
| |
| | :: BIOPERINE :: - US Patents |
| | ABSTRACT: Compositions and methods for the improvement of gastrointestinal absorption and systemic utilization of nutrients and nutritional supplements, wherein the compositions compromise a minimum of 98% of pure alkaloid piperine. | | | A new process for the extraction and purification of piperine is also disclosed. |
|
http://www.bioperine.com/us_patent.htm
|
|
| |
| | :: BIOPERINE :: - Usage & Advantages |
| | is the only product sourced out of piperine to obtain a patented status for its ability to increase the bioavailability of nutritional compounds. | | | Secondly, it is the only source from piperine to have undergone clinical studies in the U.S. to substantiate its safety and efficacy for nutritional use. |
|
http://www.bioperine.com/usage_advantage.htm
|
|
| |
| | The capacityfactor as a function of the percentage methanol |
| | Our first idea was comparing the percentages of both piperine and piperonal in the different pepper species, using HPLC. | | | This is because the quantity of ppb tasted by | | | Piperine is often used in insecticide and peppersprays. |
|
http://students.chem.tue.nl/6n220-8/capacityfactor_as_a_function_of_.htm
|
|
| |
| | Piperine multiplies the strength of many supplements and drugs |
| | Four of these mechanisms are of interest with regard to piperine: metabolic conversion, assisted absorption, assisted exclusion, and solubilizer attachment. | | | How the body controls access to its cells | | | The body has several major mechanisms for controlling the exposure of its cells to nutritional and other substances. |
|
http://www.delano.com/Articles/piperine-multiplies.html
|
|
| |
| | [No title] |
| | FIELD Accession Number:AN 1923:20781 FIELD Abstract:In view of the belief of Ott and Zimmermann (C. 16, 1229) that the sharp taste of piperine (I) in alc. | | | constitution) FIELD Index Terms(2): FIELD CAS Registry Numbers:94-62-2 (Piperine) (pepper taste of, cause of) FIELD Supplementary Terms: FIELD PCT Designated States: FIELD PCT Reg. | | | Shelf life of the fixative products were tested every 2 wk for 6 wk on their piperin content, moisture content, microbes, aroma stability, and preference test on aroma and taste. |
|
http://www.library.wisc.edu/instruction/refworks/importing/sfs_sample.txt
|
|
| |
| | SpiceLines |
| | In America and in Europe, their appeal is largely aesthetic, as they are used to add color to mixtures of black, white and green peppercorns. | | | Pepper happens to grow best in the kind of soil along India’s Malabar coast—a loamy, red “laterite” soil produced by eons of decaying rock and laden with iron and other minerals. | | | There are over 75 cultivars in India alone, which vary in oleoresin and piperine content—that is fragrance and pungency. |
|
http://www.globalprovince.com/spicelines/feature/blackpepper.htm
|
|
| |
| | Piperine Information |
| | Additionally, it is used to reduce the severity of fevers, and stomach aches by improving digestion. | | | Besides piperine and serotonin, piperine has also been shown to: help the body absorb and utilize vitamins, minerals and nutrients, such as beta-carotene (plant form of vitamin a), curcumin, selenium, pyridoxine (vitamin B6), and others. | | | Piperine has been shown to increase thermogenic activity. |
|
http://www.nutritional-supplement-info.com/piperine.html
|
|
| |
| | Hot and Spicy |
| | Piperine (Fig 1) is the active component of white and black pepper ( Piper nigrum) and is presumably of use to the plant because of its insecticidal properties (2-4). | | | The spices that we normally associate with "hot" food, such as peppers or curry, activate the warm receptors. | | | Capsaicin (pronounced cap-SAY-shin) is the substance responsible for the spiciness associated with members of the genus Capsicum, which includes most of the red and green peppers used in Mexican, South American, Cajun, and some Asian foods. |
|
http://colossus.chem.umass.edu/genchem/chem102/Articles/hotspic.htm
|
|
| |
| | British Journal of Pharmacology - Effect of vanilloid drugs on gastrointestinal transit in mice |
| | Effect of i.p.-injected anandamide and piperine on upper gastrointestinal transit. | | | The present study indicates that the vanilloid ligands anandamide and piperine, but not capsaicin, can reduce upper gastrointestinal motility. | | | It is unlikely that the vanillyl moiety is essential for this activity as both capsaicin and piperine share this chemical group. |
|
http://www.nature.com/bjp/journal/v132/n7/full/0703975a.html
|
|
| |
| | structure |
| | For example the loss of pungency of ground pepper is associated with the slow transformation of chavicine into piperine. | | | The oil in the peppercorns reacts with piperine to give it its flavor.--- When piperine looses its characteristic flavor it becomes known as Chavicine. | | | Piperine also has the less common names piperoylpiperidine, piperylpiperidine, and piperoylpiperidin |
|
http://web1.caryacademy.org/chemistry/rushin/StudentProjects/CompoundWebSites/2000/Piperine/piperin_properties_page.htm
|
|
| |
| | :: Sabinsa Corporation :: |
| | Another study confirmed for publication in early 2000 will appear in the Journal of Nutritional Biochemistry on CoQ10 and Bioperine. | | | The only clinical studies done with piperine for nutritional purposes are with Bioperine. | | | The patents awarded to Sabinsa grant the company the exclusive right to offer piperine, regardless of its source, for use in nutritional compounds. |
|
http://www.sabinsa.com/nr120699c.htm
|
|
| |
| | Chrysin / Piperine Herbal Supplements - Effects / Dose |
| | Ingredients: Chrysin (5,7-Dihydroxyflavone) is a bioflavonoid found in the plant Passiflora coerula, a member of the passion flower family. | | | The study tested the effects of these natural flavonoids (such as genistein, rutin, tea catechins, etc.) in human fat cell cultures. | | | (combined with piperine to facilitate absorption) in aging men. |
|
http://smart-herbs.com/Chrysin-herbal-supplements-piperine-effects-Dose.htm
|
|
| |
| | Pepper on Mars |
| | O and CO ices in the southern polar cap of Mars (cf News of March 17). | | | Figure 1 The piperine molecule, which can be isolated from black pepper, through extraction by ethanol. | | | The presence of piperine confirms that the red planet could have supported life eons before the present time, encouraging the hope of a future landing of humans on Mars. |
|
http://www.obspm.fr/actual/nouvelle/apr04/pepper.en.shtml
|
|
| |
| | LifeLink - Bioperine® |
| | This supplement is usually used at 5-10 mg/dose. | | | Piperine improves the absorption of these compounds in the intestine, promotes their retention in cells, and prevents their being metabolized in the liver. | | | Piperine has also shown promise as an agent for preventing diarrhea, gastric ulcers, stimulating digestive enzymes, suppressing the induction and spread of lung cancer, preventing epileptic convulsions, and stimulating melanin production. |
|
http://www.lifelinknet.com/siteResources/Products/Bioperine.asp
|
|
| |
| | Piperine definition - Medical Dictionary definitions of popular medical terms |
| | Piperine is used as a flavoring and as an insecticide. | | | Piperine: A pungent alkaloid that is concentrated in the outer skin of pepper berries (which gives pepper much of its bite) and is found in other spices and vegetables including jalapeno peppers. | | | Piperine definition - Medical Dictionary definitions of popular medical terms |
|
http://www.medterms.com/script/main/art.asp?articlekey=25033
|
|
| |
| | American Formulary Inc. > Products >CoQCare ™ |
| | Piperine acts as a bioavailability enhancer where it increases bioavailability of nutrients and drugs. | | | Piperine in AntoxCare improves the bioavailability of other ingredients in the formulation. | | | Piperine is a patented product consisting of the powdered extract obtained from Piper nigrum. |
|
http://www.americanformulary.com/coqcare.htm
|
|
| |
| | News Stories & Articles - Ayurveda / Indian Herbals / Nutraceuticals |
| | Vasakasav, Vasavaleha and Vasocin were standardised on their vasicinone and piperine content using this technique. | | | TLC method was developed for pure vasicinone and piperine which were used as standards. | | | Hence it was thought worthwhile to standardise these preparations on the basis of their vasicinone and piperine content which are the major active constituents of vasaka leaves and piper species respectively. |
|
http://www.ayuherbal.com/hptl.htm
|
|
| |
| | Indian Spices and Chinese Market |
| | These results suggest that Piperine will interact with lipid environment to lead to increased permeability of the intestinal cells. | | | Incubation of Piperine or safrole with dithionite or NADPH-reduced microsomes from untreated rats resulted in a modified type II difference spectrum with absorption maximum at 427nm and a trought at 408nm. | | | Their use in Indian medicine is due to their ability to enhance bioavailability of other medicines. |
|
http://www.indianspices.com/html/s1308mup.htm
|
|
| |
| | Enhancement of curcumin bioavailability |
| | Exp. 9: 3 grams curcumin + 20 mg piperine + 500 mg quercetin, once per day. | | | Exp. 8: 2 grams curcumin + 20 mg piperine + 500 mg quercetin, once per day. | | | Exp. 10: 3 grams curcumin + 30 mg piperine + 500 mg quercetin, once per day. |
|
http://www.delano.com/ReferenceArticles/curcumin-enhancement.html
|
|
| |
| | Molecule of the Week - Piperine |
| | Piperine has been used to treat athletes and elderly people whose ability to absorb nutrients through their intestinal lining has been impaired. | | | Piperine, an alkaloid compound found in black pepper, stimulates the body's natural ability to generate heat and assists in the absorption of selenium, vitamin B, and ß-carotene. |
|
http://www.acs.org/portal/a/c/s/1/acsdisplay.html?DOC=HomeMolecule\archive\motw_piperine_arch.html
|
|
| |
| | Physiology Online - Proceedings |
| | Piperine is a pungent alkaloid found in many species of the genus Piper. | | | Piperine, activated inward currents in HEK 293 cells expressing TRPV1 with an estimated mean EC = 38 ± 2 µ | | | Whole-cell patch-clamp recordings were made from HEK 293 cells stably expressing hTRPV1 (Hayes et al. |
|
http://www.physoc.org/publications/proceedings/archive/article.asp?ID=555PC1
|
|
| |
| | Powerful Adaptogen - Piper longum (Pippali) Extract Piperine 5% |
| | The mechanism involved seemed to be the increased secretion of protective factors like mucin and decreased cell shedding. | | | On the other hand Piperine one of the major principles of the Piper longum exerted a significant protection against tert-butyl hydroperoxide and carbon tetrachloride hepatotoxicity by reducing both in vitro and in vivo lipid peroxidation, enzymatic leakage of GPT and AP, and by preventing the depletion of GSH and total thiols in the intoxicated mice. | | | Owing to these evidences Piper longum emerges as an important Adaptogenic candidate. |
|
http://www.exoticnatural.com/adaptogen-piper.htm
|
|
| |
| | Kalsec - Black and White Pepper Extracts |
| | Homogeneous, oil and water dispersible extracts consisting of a crystalline suspension of piperine in fixed and essential oils of black pepper and significantly reduced in chlorophyll content. | | | Homogeneous, oil dispersible extracts consisting of a crystalline suspension of piperine in fixed and essential oils of black pepper and significantly reduced in chlorophyll content. | | | Homogeneous, oil and water dispersible extracts consisting of a crystalline suspension of piperine in fixed and essential oils of black pepper. |
|
http://www.kalsec.com/products/bandwpepper_pg.cfm
|
|
| |
| | British Journal of Pharmacology - Abstract of article: Effects of piperine, the pungent component of black pepper, at ... |
| | Piperine produced a clear agonist activity at the human TRPV1 receptor yielding rapidly activating whole-cell currents that were antagonised by the competitive TRPV1 antagonist capsazepine and the non-competitive TRPV1 blocker ruthenium red. | | | Although piperine was a less potent agonist (EC) than capsaicin (EC), it demonstrated a much greater efficacy (approximately two-fold) at TRPV1. | | | Effects of piperine, the pungent component of black pepper, at the human vanilloid receptor (TRPV1) |
|
http://www.nature.com/bjp/journal/v144/n6/abs/0706040a.html
|
|
| |
| | Piperine |
| | It has also been used in some forms of traditional medicine and as an insecticide. | | | Piperine is the alkaloid responsible for the taste and smell of the spice pepper. |
|
http://www.worldhistory.com/wiki/P/Piperine.htm
|
|
| |
| | IngentaConnect COMPARATIVE ANTI-NOCICEPTIVE, ANTI-INFLAMMATORY AND TOXICITY PROF... |
| | Piperine is an inhibitor of various hepatic and other enzymes involved in the biotransformation of drugs. | | | The present study was, thus, conducted to evaluate the antinociceptive, anti-inflammatory and toxicity profile of a new nimesulide–piperine combination administered orally as compared with nimesulide alone. | | | Preliminary pharmacokinetic studies conducted by us suggested the increased bioavailability of nimesulide co-administered with piperine. |
|
http://www.ingentaconnect.com/content/ap/fr/2000/00000041/00000006/art00640
|
|
| |
| | Vitamin Express Brain Flex Information |
| | It acts as a thermonutrient which may accelerate the body's intake of nutrients. | | | CoQ10, when combined with carnitine, appears to work synergistically. | | | - a form of piperine which comes from the black pepper plant. |
|
http://www.vitaminexpress.com/prodinfo/VEBrainFlex.htm
|
|
| |
| | Genesis Health System - Alternative Medicine Interactions Information - Piperine |
| | At the time this document was written, no interactions between PIPERINE and food were found. | | | Taking PIPERINE and seizure medicines together may increase the chance of side effects including dizziness, itchiness, low blood pressure, and increased heat rate. | | | If you are already taking PIPERINE and seizure medicines together and have dizziness, itchiness, low blood pressure, or increased heat rate, call your doctor right away. |
|
http://www.genesishealth.com/micromedex/altmedint/ci0031.aspx
|
|
| |
| | C251.01 Lab -- Piperine Project |
| | Piperine is a component of black pepper which causes sneezing. | | | Its presence in pepper was discovered many years ago, and its structure was elucidated near the beginning of the century. |
|
http://www.ups.edu/faculty/hanson/c251lab.01/piperine.htm
|
|
| |
| | Piperine |
| | Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers - Planta Med. | | | 1998 May;64(4):353-6 - "Concomitant administration of piperine 20 mg produced much higher concentrations from 0.25 to 1 h post drug (P < 0.01 at 0.25 and 0.5 h; P < 0.001 at 1 h), the increase in bioavailability was 2000%. | | | These compounds have been reliably shown to increase testosterone and reduce excess estrogen, resulting in a youthful hormone profile that optimizes immune function and to some degree, body composition" |
|
http://qualitycounts.com/fppiperine.htm
|
|
| |
| | budster ^5 chili |
| | This is familiar to most 'chile-heads' as an increasing ability to eat hotter chile peppers and foods. | | | Pure capsaicin, or 8-methyl-n-vanillyl-6-nonenamide, is a whitish powder which is soluble in alcohol but insoluble in cold water, which is why drinking water to help alleviate the burning won't work. | | | The capsaicinoids are unique compared to other "spicy" substances such as mustard oil (zingerone and allyl isothiocyanate), black pepper (piperine) and ginger (gingerol) in that capsaicin causes a long-lasting selective desensitization to the irritant pain by repeated doses of a low concentration or a single high concentration dose. |
|
http://members.tripod.com/~B_u_d/chili.html
|
|
| |
| | Cole-Parmer: Piperine - EW-88134-21 |
| | Cole-Parmer Catalog > Chemicals > Chemicals P > Phthala to Plas > Piperine | | | Piperine, from Piper Nigrum (black pepperseeds) 99% (5g) |
|
http://www.coleparmer.com/catalog/product_view.asp?referred_id=168&sku=8813421
|
|
| |
| | www.modernnatural.biz |
| | Piperine: 90-95% - UV Spectrophotometric method - SIC/Q.M/206 | | | Spice Equivalent: One kg replaces 50 kg of black pepper powder. |
|
http://modernnatural.biz/Oleoresins-Piperine.htm
|
|
| |
| | Merriam-Webster Online |
| | For More Information on "piperine" go to Britannica.com | | | Get the Top 10 Search Results for "piperine" |
|
http://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=piperine
|
|
|
